產(chǎn)品編號(hào) yb-2532R
英文名稱 Anti-ALT1抗體
中文名稱 谷*氨基轉(zhuǎn)移酶1抗體
別    名 Alanine aminotransferase; AAT 1; AAT1; Alanine aminotransferase 1; alanine aminotransferase; ALT 1; ALT1; Glutamic alanine transaminase 1; Glutamic pyruvate transaminase; Glutamic pyruvic transaminase 1; Glutamic-alanine transaminase; GPT 1; GPT; GPT1; SGPT; ALAT1_HUMAN.
Anti-ALT1抗體  
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Pig, Cow, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 55kDa
細(xì)胞定位 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ALT1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Alanine Transaminase [glutamic pyruvate transaminase - GPT] participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles. Pyridoxal phosphate is a known cofactor. Expression is induced by glucocorticoids. This enzyme is present in a high concentration in liver tissue and it's release into the blood indicates liver disease or damage.

Function:
Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Liver, kidney, heart, and skeletal muscles. Expressed at moderate levels in the adipose tissue.

Similarity:
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.