產品編號 yb-0537R
英文名稱 Anti-ANGPTL2抗體
中文名稱 血管生成素樣蛋白2抗體
別    名 ANGPTL2; Angiopoietin like 2; Angiopoietin related protein 2; Angiopoietin-like protein 2; Angiopoietin-related protein 2; ANGL2_HUMAN; Angptl2; ANGL2; Arp2; HARP; MGC8889.
 Anti-ANGPTL2抗體  
說 明 書 0.1ml  0.2ml  
研究領域 腫瘤  心血管  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 55kDa
細胞定位 分泌型蛋白 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ANGPTL2 C-terminus
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
 
PubMed PubMed
產品介紹 background:
ANGPTL2/ANG-2 (Angiopoietin-like Protein 2) Induces sprouting in endothelial cells through an autocrine and paracrine action. [Subcellular location] Secreted. [Tissue specificity] Widely expressed in heart, small intestine, spleen and stomach. Also found in lower levels in colon, ovary, adrenal gland, skeletal muscle and in prostate. [PTM] N-glycosylated. [Similarity] Contains 1 fibrinogen C-terminal domain. ANGPTL2/ANG-2 (Angiopoietin-like Protein 2).


Function:
Induces sprouting in endothelial cells through an autocrine and paracrine action.

Subcellular Location:
Secreted.

Tissue Specificity:
Widely expressed in heart, small intestine, spleen and stomach. Also found in lower levels in colon, ovary, adrenal gland, skeletal muscle and in prostate.

Similarity:
Contains 1 fibrinogen C-terminal domain.

 
Ang1/2與血管生成關系zui為密切,目前有關該家族成員在腫瘤血管生成中的研究正日益增多。近年來也用于糖尿病導致的血管損傷研究也是熱門課題.