產(chǎn)品編號(hào) yb-0090R
英文名稱 Anti-ADM R抗體
中文名稱 腎上腺髓質(zhì)素受體抗體
別    名 Adrenomedullin Receptor L1; 7TMR; ADMR; adrenomedullin receptor; AM R; AMR; G protein coupled receptor 182; Gamrh; GPR 182; GPR182; hrhAMR; MGC34399.
Anti-ADM R抗體
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  內(nèi)分泌病  新陳代謝  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse ADM R
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Adrenomedullin is a potent vasodilator peptide that exerts major effects on cardiovascular function. This gene encodes a seven-transmembrane protein that belongs to the family 1 of G-protein coupled receptors. Studies of the rat counterpart suggest that the encoded protein may function as a receptor for adrenomedullin. [provided by RefSeq, Jul 2008] 

Function:
Orphan receptor.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Highly expressed in heart, skeletal muscle, immune system, adrenal gland and liver.

Similarity:
Belongs to the G-protein coupled receptor 1 family.


腎上腺髓質(zhì)素受體是一個(gè)由395個(gè)氨基酸組成的，分子中包括七個(gè)跨膜區(qū)，屬G-蛋白家族。在肺部分布豐富。